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Clients were treated with additional ray radiotherapy (EBRT) (57%), locoregional treatment of distant metastases (41%), cytotoxic chemotherapy (38%) and tyrosine kinase inhibitors (TKIs) (33%). TKI treatment resulted in median infection control duration of 7 months with a grade 3-4 toxicity rate of 44%. Only 1 client had a total thyroidectomy after neo-adjuvant EBRT. The 1, 3 and 5-year collective survival rate was 81%, 27.7% and 21.5%, respectively. The cause of dea