https://www.selleckchem.com/pr....oducts/puromycin-ami
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools. We established and characterized human NN (hNN) from hiPSC-derived neural progenitor cells by comparing hNN formation with two different differentiation media in presence (CINDA) and absence (neural differentiation medium (NDM)) of maturation-supporting factors. As a NN con