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Carriers were more likely to have upper respiratory (URI) symptoms [odds ratio (OR) 5.5; 95% confidence interval (CI) 1.4-22.1], headache (OR 6.0; 95% CI 1.2-40.5) or vomiting (OR 5.5; 95% CI 1.2-24.5). Cohort 2 (N = 122 illness cultures) 79% were acutely infected and 21% were carriers. Children determined to be carriers with a previous detected emm-type were more likely to have URI symptoms compared with those with acquisition of a new emm-type. CONCLUSIONS Children with symptomatic pharyngitis and GAS on throat culture identified as carri
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