https://www.selleckchem.com/pr....oducts/protac-tubuli
BACKGROUND Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency (MCADD) is the most frequent fatty acid oxidation (FAO) defect in humans. MCAD-deficient fibroblasts are more resistant to oxidative stress-induced cell death than other FAO defects and healthy controls. METHODS Herein we investigate the antioxidant response and mitochondrial function in fibroblasts from MCAD-deficient patients (c.985 AG/c.985 AG) and healthy controls. RESULTS MCAD-deficient fibroblasts showed increased level of mitochondrial supe
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