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Concordance of cfDNA with standard microbiological culture of contemporaneously collected patient sputum was variable. Our findings provide evidence that cfDNA from respiratory pathogens are present in the bloodstream of most CF patients, which could potentially be exploited for the purposes of noninvasive clinical diagnosis.An amendment to this paper has been published and can be accessed via a link at the top of the paper.BACKGROUND There is concern that African-American men (AA) with low-risk prostate cancer may present with more ag