https://www.selleckchem.com/pr....oducts/mk-5108-vx-68
Several observational studies have shown that the inappropriate dosing use of direct oral anticoagulants (DOACs) in atrial fibrillation (AF) that does not conform to recommendations is becoming a widespread phenomenon. Therefore, we performed a meta-analysis and systematic review to assess the effect of non-recommended doses versus recommended doses of DOACs on the effectiveness and safety outcomes among AF patients. The PubMed and Ovid databases were systematically searched to identify the relevant studies until December 2020. T