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42 ± 393.42 ml vs. 1150.02 ± 416.1 ml) ( = 0.02). The quality of the surgical field was better in the tranexamic group (median score 4 vs. 2 on Likert Scale) ( 0.001). Patients in tranexamic group had an improved coagulation profile and decreased blood transfusion requirement (p=0.016). The blood collected in closed suction drain in 24 h postsurgery was less in the tranexamic acid group compared to placebo group (84.7 ± 50.4 ml vs. 127.6 ± 62.2 ml) ( = 0.047). Tranexamic acid bolus followed by infusion reduces perioperative blood l