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Prosthetic joints are at risk of becoming infected during an episode of bacteremia, especially during S. aureus bacteremia. However, it is unclear how often asymptomatic PJI occurs and whether additional diagnostics should be considered. In this multicenter study, we retrospectively analyzed a cohort of patients with a late acute (hematogenous) PJI between 2005-2015 who had concomitant prosthetic joints in situ. Patients without at least 1 year of follow -up were excluded. 91 patients with a hematogenous PJI and 108 concomitant prosthet