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How Does ADHD Medication Work? Many people have found that ADHD medication helps them concentrate, focus and manage their unpredictable behavior. It can be a long process to find the right medication and dosage for each individual. Certain medications can affect children's sleeping patterns. If they are sleeping better, this is a sign that the medication is working. 1. Stimulants Stimulants are among the most commonly prescribed prescription medications that healthcare professionals use to treat ADHD