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Treating ADHD Without Medication Many people with ADHD find that treating their symptoms with no medication is successful. Combining psychotherapy, behavior change and natural remedies is often the best solution. Methylphenidate boosts certain brain chemicals that regulate impulses and attention. There are also non-stimulants such as guanfacine or atomoxetine. Psychotherapy, exercise and good sleep habits can all help. Some patients with ADHD also have coexisting conditions su