https://www.selleckchem.com/pr....oducts/prt062607-p50
Cell therapy using hepatocytes derived from stem cells has been regarded as a promising alternate to liver transplantation. However, the heterogeneity of these hepatocytes makes them unsuitable for therapeutic use. To overcome this limitation, we generated homogenous hepatocyte like induced hepatocyte-like (iHep) cells. iHep cells were generated from induced pluripotent stem cells (iPSCs) integrated with the albumin (AL reporter gene. The therapeutic properties of these iHep cells were investigated after transplantation