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Collectively, in this study, we very first demonstrated that IGF1 enhances BM-MSC-mediated wound recovery as well as hair hair follicle regeneration. Our data claim that the topical application of IGF1 and BM-MSCs incorporated in collagen-chitosan scaffolds may be used as a feasible and efficient healing strategy to enhance functional cutaneous wound healing. Cerebral ischemia/reperfusion (I/R) damage is an extreme complication through the treatment of patients with stroke. It is often shown t