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The numbers of inflammatory cells were significantly higher in the scleral grafts ( 0.05), and CD3 T cells and CD34 cells were populated within inflammatory cells at graft-recipient junctions in both groups. The mean areas of the estimated perigraft and intragraft neovascularization tended to be higher in scleral grafts. Preserved corneal lamellar grafting enhances epithelial wound healing and alleviates inflammation in a scleral defect rabbit model. This work suggests that the preserved corneal graft may be considered as a favorab