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Twelve clients (group 1) had lymphoplasmocytic, non-transformed cutaneous expansion, whilst in 7 cases (group 2) cutaneous participation corresponded to histological change. In-group 1, epidermis participation was inaugural in 6 instances. The lesions had been infiltrated plaques (83%), papules (25%) and tumours (42%). Four patients had a similar medical picture (purplish, bilateral and shaped infiltration in the face). MYD88 L265P mutation had been