https://www.selleckchem.com/pr....oducts/aminoguanidin
. The American Society for Pharmacology and Experimental Therapeutics.Proteinase-Activated Receptors (PARs) are a four-member family of G-protein coupled receptors that are activated via proteolysis. PAR4 is a member of this family that is cleaved and activated by the serine proteinases such as thrombin, trypsin and cathepsin-G. PAR4 is expressed in a variety of tissues and cell types including the platelets, vascular smooth muscle cells and neuronal cells. In studying PAR4 signaling and trafficking, we observed dyn
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