https://nsc697855inhibitor.com..../selfish-genetic-ele
In this research, we have carried out long-time atomistic molecular dynamics simulations (1 μs for each system) for MT patches as well as a brief portion of a closed MT both in GTP- and GDP-bound states. Our results confirmed that MTs within the GDP state generally have weaker lateral interactions between neighboring protofilaments (PFs) much less cooperative outward bending conformational change, where difference between bending sides of neighboring PFs is often larger compared with GTP ones. Because of
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