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PTEN was a target of miR-181a. Inhibition of miR-181a remarkably corrected MF-triggered effects on ATDC5 cells. Conclusion MF attenuated LPS-induced inflammatory harm through miR-181a/PTEN axis and thereby inhibiting NF-κB path and activating PI3K/AKT pathway. Copyright laws © 2020 Ma, Liu, Ma, Jiang, Wang, Wang, Niu, Hu, Lin and Yu.Ischemic heart disease (IHD), caused predominantly by atherosclerosis, is a number one reason for worldwide mortality. Our previous studies showed that Shenlian ext