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954-0.977; P ≤ 0.001) and female (OR = 0.667, 95% CI 0.451-0.986, P = 0.042) were independent risk factors for preoperative DVT in the uninjured lower extremity. Blood loss (OR = 0.997, 95 CI% 0.995-1.000; P = 0.02, D-dimer level at admission (OR = 0.941, 95 CI% 0.887-0.999; P = 0.045), and postoperative day 5 D-dimer level (OR = 0.889, 95 CI% 0.819-0.965; P = 0.005), were independent risk factors for postoperative DVT in the uninjured lower extremity. For the patients with lower extremity fractures, age and female were associated w