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Unexpectedly, we found preferential rearrangement of the non-canonical IgHV-TCRδC over canonical TCR αδV-TCRδC receptors. The differential use of SHM may reveal how AID targets V regions. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.INTRODUCTION Invasive prenatal testing with chromosomal microarray analysis may be a relevant option for all pregnant women, but there is only moderate-quality evidence for such an offer. We intended to study the prevalence of copy