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These substances integrated five of the six clusters. One of the groups (insufficient level of physical activity during leisure time + consumption of alcoholic beverages + use of cigarettes and illicit drugs) had an upward trend throughout the series. The trend analysis showed four out of six clusters remaining stable throughout the series, which shows that the factors are persistently present among school adolescents. The trend analysis showed four out of six clusters remaining stable throughout the series, which shows that the factor