https://www.selleckchem.com/pr....oducts/telotristat-e
Conventional thin (0.4mm) and thick (0.6mm) slices were obtained using a vibratome and pretreated with mACSF at 35-36°C for 1h prior to recordings. During perfusion with mACSF at 35-36°C, spontaneous or self-sustained epileptiform field potentials following high-frequency stimulation were frequently recorded in slices pretreated with mACSF but not in those without the pretreatment. Seizure-like ictal discharges were more common in thick slices than in thin slices. Prolonged exposure to mACSF by pretreatmen