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BACKGROUND Vitamin D exerts multiple pleiotropic effects beyond its role in calcium-phosphate metabolism. Growing evidence suggest an association between hypovitaminosis D and sleep disorders, thus increasing the interest on the role of this vitamin in the regulatory mechanisms of sleep-wake cycle. OBJECTIVE To explore and summarize the current knowledge about the role of vitamin D in sleep regulation and the impact of vitamin D deficiency on sleep disorders. METHODS The main regulatory mechanisms of vitamin D on sleep are explained. The