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Organic matter removal was 18% higher in closed-circuit mode than in open-circuit mode in both integrated systems (P-CWMFC and NP-CWMFC), and these differences were significant (p less then 0.05). With respect to the performance of microbial fuel cells, the maximum power density (8.6 mW/m2) was achieved at an organic loading rate of 7.9 g COD/m2 d with an internal resistance and coulombic efficiency of 251 Ω and 2.4%, respectively. The results obtained in this work can provide positive impacts on CW development by enhancing anaerobic d