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ADHD Medications For Adults Stimulants aid in adjusting the levels of chemical messengers in the brain that control attention. They are first-line medications for treating ADHD. Although they're not in any way habit-forming, they can trigger adverse effects like headaches and trouble sleeping. Your doctor might prescribe Guanfacine (brand names Tenex and Intuniv) or clonidine (Catapres) to decrease the impulsivity and hyperactivity. These medications are more effective than st