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ht hemispheric predominance may be explained by an early insult, likely genetically determined, on brain morphogenesis. To improve epidemiologic knowledge of neurologic deterioration (ND) in patients with acute ischemic stroke (AIS). In this prospective observational study, we captured ND prospectively in 29,446 patients with AIS admitted to 15 hospitals in Korea within 7 days of stroke onset. ND was defined as an increase in NIH Stroke Scale (NIHSS) score ≥2 (total), or ≥1 (motor or consciousness), or any new neurologic symptoms. Chang
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