https://www.selleckchem.com/pr....oducts/eapb02303.htm
23 ppm in the 1H NMR spectra confirmed the imine proton of Schiff base. The cytotoxicity of Chitosan, Chitosan-Schiff base and its metals complexes was tested against K562 chronic myelogenous leukemia (CML) and MG-63 (osteosarcoma cancer) cell lines by the MTT assay. The results suggested that the anticancer activity of Schiff base and their complexes was much better than that of pure CS against cancer MG63 cell line. Finally, through flow cytometry, we demonstrated that all compounds were efficient in inducing apoptosis effect in K56
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