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51 (95% CI, 116.61 to 130.42) in the acupuncture group and 94.73 (95% CI, 85.03 to 104.43) in the PEG 4000/pinaverium bromide group. The between-group difference was 28.78 (95% CI, 16.84 to 40.72; P less then .001). No participant experienced severe adverse effects. Conclusion Acupuncture may be more effective than PEG 4000 or pinaverium bromide for the treatment of IBS, with effects lasting up to 12 weeks. Trial registration Chinese Clinical Trials Register, ChiCTR-IOR-15006259.Transcatheter aortic valve replacement (TAVR) offers well
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