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New strategies using big data may help to clarify these questions easily and in a most cost-effective approach.INTRODUCTION This retrospective cohort study evaluated the impact of endometriosis on the risks of work loss events and salary/growth over a 5-year period. METHODS Women aged 18-49 years with ≥ 1 endometriosis diagnosis were identified in a claims database and matched 11 to women without endometriosis (controls). The index date was the first endometriosis diagnosis date (endometriosis cohort) or a random date duri