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Furthermore, PRC2 binding led to a 3-fold increase in your local bending of DNA's helical backbone without evidence of DNA wrapping round the protein. We declare that the bending and looping of DNA by PRC2, separate of PRC2's methylation activity, may play a role in heterochromatin formation and so epigenetic gene silencing. Posted by Oxford University Press on behalf of Nucleic Acids Research 2020.BACKGROUND Key measurements of cardiac arrest-induced posttraumatic stress disorde