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While for Pb2+ removal, besides the released OH- from LDO as precipitate agent, the vacancy defect resulting from the S doping played a crucial role in electron interaction between Pb2+ and S-doped graphene. Additionally, the MG/S-LDO was further confirmed as an eco-friendly adsorbent with excellent reusability via the acute toxicity tests using green algae and multiple cycle experiments. This work provides a novel resource-utilization strategy for organic layered wastes to construct the functional eco-friendly materials in wastewater pu