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7% of patients displaying elevated IL-6 levels and 80.8% of patients displaying a reduced level of low-density lipoprotein cholesterol (LDL-C). In the present single-center case study of 78 patients with COVID-19 in Wuhan, China, the patients displayed abnormal routine blood tests, liver function, renal function and levels of D-dimer, LDL-C and IL-6. Therefore, the development of drugs and vaccines that can be used to prevent and treat infections of COVID-19 is urgently required.The present study aimed to explore the role of TGF-β1-media