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01) and a 3.12-fold ([1.44-6.75]; = 0.004) greater risk of death at 1 year from second eGFR measurement. In patients with HFrEF diabetes and male sex are independent predictors of a decline in eGFR at 1 year. A decline eGFR over 1 year is associated with higher long-term all-cause mortality. In patients with HFrEF diabetes and male sex are independent predictors of a decline in eGFR at 1 year. A decline eGFR over 1 year is associated with higher long-term all-cause mortality.Integrative physicians (IPs) working in supportive and pallia