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They have tiny resemblance to one another and cannot be easily identified utilizing simple search algorithms such as for example BLAST and PSI-BLAST. Different AFPs found in fishes (Type I, II, III, IV and antifreeze glycoproteins (AFGPs)), are sub-types and show low sequence and structural similarity, making their particular accurate prediction challenging. Although several machine-learning methods have been suggested for the category of AFPs, forecast
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