https://www.selleckchem.com/pr....oducts/Calcitriol-(R
BACKGROUND Sustained adrenergic signaling secondary to chronic stress promotes cancer progression; however, the underlying mechanisms for this phenomenon remain unclear. Hepatocellular carcinoma (HCC) frequently develops within fibrotic livers rich in activated hepatic stellate cells (HSCs). Here, we examined whether the stress hormone norepinephrine (NE) could accelerate HCC progression by modulating HSCs activities. METHODS HCC cells were exposed to conditioned medium (CM) from NE-stimulated HSCs. The changes in cell mi
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