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CA also restored altered elemental levels in brain tissues. These results indicate the stimulatory potential of CA on brain glucose utilization with simultaneous neuroprotective activities. What is the central question of this study? How does acute hypoxia alter central and peripheral fatigue during brief and sustained maximal voluntary muscle contractions? What is the main finding and its importance? Perception of fatigue during muscle contractions was increased progressively for 2 h after hypoxic exposure. However, an increase in motor