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Choices have to be made regarding what reference mortality rates to use and what age distribution to standardize to. We illustrate the method and some potential choices using data from England for men diagnosed with melanoma. Various marginal measures are presented and compared. The new measures help enhance understanding of cancer survival and are a complement to the more commonly used measures. The new measures help enhance understanding of cancer survival and are a complement to the more commonly used measures. Remdesivir is a prodrug