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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD experience improvements in their symptoms by taking medication. But every person reacts differently to different drugs and adverse effects can be a problem. Methylphenidate is a stimulant. It works by raising levels of a chemical in the brain that aids in controlling the behavior and attention. Stimulant medication Stimulant drugs enhance attention and concentration in 70 to 80percent of children and adults who use them. They work by altering neurotransmitters, such as nor