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6% experienced fracture at 24 months (women vs men 12 months, 4.8% vs 2.5%; 24 months, 8.3% vs 4.4%; both P less then .01). At 12 months, recent fracture conferred approximately 3-fold-higher fracture risk (vs no recent fracture). Older age, white race, female sex, osteoporosis-related screening/diagnosis/medication, antidepressant/antipsychotic/sedative hypnotic/muscle relaxant medications, history of falls, fracture history, and respiratory conditions also increased risk (all P less then .0001). The simplified model (recent fracture, age