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score were associated with worse overall survival (all 0.001). Multivariate analysis showed that low MVV and the HALP score were both independent risk factors for overall survival (all 0.001). The combination of MVV and HALP score improved the prediction performance for overall survival than tumor-node-metastasis. Also, low combination of MVV and HALP score was an independent risk factor for poor overall survival ( 0.001). MVV, HALP score and their combination are simple and promising clinical markers to predict ove