https://www.selleckchem.com/pr....oducts/dapansutrile.
CONCLUSIONS We found that SCAT ANGPTL4 was closely linked with the expression of ANGPTL4 in the liver and represented a good proxy for liver steatosis. We suggest the elevation of ANGPTL4 levels in diabetes and the association with inflammation and hypoxia is due to a compensatory mechanism to limit further AT dysfunction. A reduction of ANGPTL4 for the treatment of T2DM as previously suggested is thus unlikely to be of further benefit. BACKGROUND Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty a