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679, 0.621, and 0.620, respectively) with high negative predictive value (96.6%, 95.1%, and 93.1%, respectively). Multivariate analysis revealed the different effects of individual criteria on bleeding events in each follow-up period. The ARC-HBR definition consistently identified patients at risk of long-term bleeding and ischemic events after second-generation DES implantation. The ARC-HBR definition consistently identified patients at risk of long-term bleeding and ischemic events after second-generation DES implantation. Pulmonary