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Outcomes are being measured at baseline, 2 months, 3 months and 6 months. The primary analysis tool will be linear mixed effects model. The prespecified inferiority margin for the primary outcome is 10 points. We will also examine whether baseline characteristics (eg, sociodemographic) moderate outcomes of the intervention and whether changes in self-efficacy and fatigue self-management behaviours mediate changes in outcomes. The protocol is approved centrally by the institutional review board at Case Western Reserve University. Eligible
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