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How Does Medication For ADHD Work? Stimulants boost the levels of norepinephrine and dopamine in your brain, helping improve attention and impulse control. They are available in both immediate-release (short acting) and extended release tablets, which can be taken once daily in the morning. Nonstimulant medicines can enhance the ability to control impulses and attention however, they take longer to work. Atomoxetine, Viloxazine and guanfacine are antidepressants tha