https://www.selleckchem.com/pr....oducts/icec0942-hydr
Human bronchial epithelial cells were exposed to TDI or vehicle. Results TDI-exposed mice had higher numbers of airway goblet cells, BAL eosinophils, CD4+ T cells and ILC, with a predominant type 2 response and tended to have airway hyperresponsiveness. In TDI-exposed microRNA-155 knockout mice, inflammation and airway hyperresponsiveness was attenuated. TDI exposure induced IL-33 expression in human bronchial epithelial cells and in murine lungs, which was microRNA-155 dependent in mice. GATA3+CD3- cells, presumably ILC2
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