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49 to - 3.40, P less then 0.0001) were significantly lower in VATS segmentectomy patients. CONCLUSIONS VATS segmentectomy and VATS lobectomy provide similar oncological and perioperative outcomes for stage I NSCLC patients. This systematic review was registered on PROSPERO and can be accessed at http//www.crd.york.ac.uk/PROSPERO/display_record.php?ID = CRD42019133398.BACKGROUND The cytokine IL-17 is a key player in autoimmune processes, while the cytokine IL-6 is responsible for the chronification of inflammation. However, their roles