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PURPOSE To evaluate the performance of an artificial intelligence (AI) based software solution tested on liver volumetric analyses and to compare the results to the manual contour segmentation. MATERIALS AND METHODS We retrospectively obtained 462 multiphasic CT datasets with six series for each patient three different contrast phases and two slice thickness reconstructions (1.5/5 mm), totaling 2772 series. AI-based liver volumes were determined using multi-scale deep-reinforcement learning for 3D body markers detection and 3D structure