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•The CDC's cumulative funding for Public Health, Prevention, and Emergency Preparedness decreased over the course of 2011-2020, however, NIH funding dedicated to Prevention displayed an overall increase from 2008 to 2019.•The Hospital Preparedness Program (HPP) is the only source of federal funding for healthcare system readiness, yet their budget exhibited consistent reductions from 2003 to 2018.•Public health emergencies like the COVID-19 pandemic have demonstrated more significant consequences than other diseases that receiv