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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a range of issues for adults. This includes issues with work, relationships and mental health. Adults suffering from untreated ADHD typically have low self-esteem, and have a negative outlook on the world. This can make them feel as if they are failing at home and work. Lack of Focus Finding it difficult to stay focused at times is normal, especially after a long day at work or school. If you are noticing that your abili