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Outcomes from simulated glucose clamps also agree quantitatively with current GRI publications. We illustrate that the design can be used to explore the vast number of permutations constituting the GRI parameter space, and thus determine the perfect design ranges that give desired overall performance. A design guide aside, PAMERAH moreover can facilitate GRI's medical interpretation by connecting each applicant's efficacies in rats, mice, and humans. The resultant mapping helps discover GRIs
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