https://www.selleckchem.com/pr....oducts/hydroxychloro
The median arterial wall thickness and area/diameter ratio reduced significantly in treatment group compared to untreated hypertension group (P 0.05). Wire myography demonstrated increased relaxation of mesenteric artery with increase in concentration of ML213. A significant up-regulation in the expression of all Kv7 mRNA subunits was observed in allisartan group compared to untreated hypertension group. From the results, allisartan was found to lower BP and preserve vascular remodeling through Kv7 channels. From